@article {498791,
	title = {Convergence to the island-model coalescent process in populations with restricted migration},
	journal = {Genetics},
	volume = {172},
	number = {1},
	year = {2006},
	note = {<p>wakeley@fas.harvard.edu</p>},
	pages = {701-708},
	abstract = {<p>In this article we apply some graph-theoretic results to the study of coalescence in a structured population with migration. The graph is the pattern of migration among subpopulations, or demes, and we use the theory of random walks on graphs to characterize the ease with which ancestral lineages can traverse the habitat in a series of migration events. We identify conditions under which the coalescent process in populations with restricted migration, such that individuals cannot traverse the habitat freely in a single migration event, nonetheless becomes identical to the coalescent process in the island migration model in the limit as the number of demes tends to infinity. Specifically, we first note that a sequence of symmetric graphs with Diaconis-Stroock constant bounded above has an unstructured Kingman-type coalescent in the limit for a sample of size two from two different demes. We then show that circular and toroidal models with long-range but restricted migration have an upper bound on this constant and so have an unstructured-migration coalescent in the limit. We investigate the rate of convergence to this limit using simulations.</p>},
	keywords = {Behaviour, Genetic techniques, Genetics, Techniques},
	author = {Matsen, FA and J. Wakeley}
}
